Onco Life Hospitals

Hereditary Breast Cancer: Surgical Strategies for High-Risk Patients

Hereditary or familial breast cancer accounts for a significant percentage of all breast cancer cases, with genetics playing a pivotal role in determining risk. It is estimated that approximately 10% of all breast cancers are linked to the inheritance of mutated breast cancer genes, especially mutations in the BRCA1 and BRCA2 genes. For patients with such a family history of breast cancer, surgical intervention is often a key component of their treatment strategy. Consulting with an experienced breast cancer surgeon in pune is therefore crucial for these high-risk patients to navigate their surgical options and manage their risk effectively.

Understanding Hereditary Breast Cancer

Hereditary breast cancer is primarily linked to mutations in the BRCA1 and BRCA2 genes, which significantly increase the risk of developing breast and ovarian cancers. Women with these mutations may face a lifetime breast cancer risk of up to 70%. Identifying these genetic mutations early on is crucial and can lead to proactive measures to reduce the risk of cancer development. Genetic testing is a crucial tool for detecting these mutations and guiding preventative strategies. Individuals with a family history of breast or ovarian cancer, especially those with multiple relatives affected, should consider genetic testing to assess their risk.

The Role of a Breast Cancer Surgeon

A breast cancer surgeon plays a critical role in the treatment and management of hereditary breast cancer. These specialists are trained to perform surgeries that not only remove existing cancer but also reduce the risk of future cancer development. Here are some key surgical strategies used by breast cancer surgeons for high-risk patients:

Prophylactic Mastectomy

For high-risk patients, a prophylactic mastectomy, or preventive mastectomy, is often recommended. This surgery involves the removal of one or both breasts to significantly reduce the risk of developing breast cancer. Studies have shown that prophylactic mastectomy can reduce the risk of breast cancer by up to 95% in women with BRCA1 or BRCA2 mutations.

Breast-Conserving Surgery

In cases where the cancer is detected early, breast-conserving surgery (BCS), also known as a lumpectomy, may be an option. A breast cancer surgeon will remove the tumor and a small margin of surrounding tissue, preserving as much of the breast as possible. The surgeon could additionally remove some lymph nodes under the arm since breast cancer often metastasizes to the lymph nodes. Breast conserving surgery is often followed by radiation therapy to ensure the elimination of any remaining cancer cells and to decrease the risk of cancer recurrence.

Reconstructive Surgery

For many patients undergoing breast cancer surgery, breast reconstruction is an important part of the surgical process. A breast cancer surgeon can work closely with a plastic surgeon to plan and execute reconstructive surgery, which can be performed immediately following a mastectomy or at a later date. Reconstructive surgery helps restore the appearance of the breast, improving the patient’s quality of life and psychological well-being.

Personalized Surgical Plans

Every patient’s situation is unique, and a breast cancer surgeon will develop a personalized surgical plan tailored to the individual’s risk factors, preferences, and overall health. Factors such as the patient’s age, genetic profile, and personal preferences are all taken into account when designing a treatment strategy.


For high-risk patients, surgical strategies are a critical component of managing hereditary breast cancer. By working with a skilled breast cancer surgeon, patients can explore options like prophylactic mastectomy, breast-conserving surgery, and reconstructive surgery to reduce their risk and improve their outcomes. These specialists can also provide detailed information on the risks and benefits of each surgical option, helping patients make informed decisions about their care.

If you or a loved one are at high risk for breast cancer, consulting with a breast cancer surgeon at Onco-Life Cancer Center can provide you with the expert guidance and care you need.

At Onco-Life Cancer Center, our team of experienced Breast Oncology Specialists is dedicated to providing personalized, compassionate care to patients. Our expert team, predominantly composed of female specialists, ensures patient comfort from diagnosis through treatment. As pioneers in breast oncology in Pune, Mumbai and surrounding areas, we aim to provide highly effective breast cancer treatment at affordable rates. Contact us to schedule a consultation and to learn more about your surgical options for managing hereditary breast cancer.

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